本計畫主要目的是要(1)進行關注化學物質於臺灣本島主要15條河川環境流布調查、(2)針對特定河川及特定化學物質流布途徑進行模擬研析與(3)化學物質環境流布管理決策分析平台建置。已完成淡水河本流、大漢溪、新店溪、基隆河、大甲溪、濁水溪、八掌溪、急水溪、將軍溪、曾文溪、高屏溪、林邊溪、花蓮溪、秀姑巒溪、卑南溪等15條河川之底泥及魚體採樣及分析，檢測項目包括，六氯丁二烯(HCBD)、短鏈氯化石蠟(SCCPs)、壬基酚(NP)及雙酚Ａ(BPA)、鄰苯二甲酸酯類(PAEs)、多溴二苯醚類(PBDEs)及六溴聯苯類(HBBs)、多環芳香烴化合物(PAHs)、重金屬及甲基汞等7類97種檢測物質，獲得16,005筆樣本檢測數據。環境流布調查結果發現多項化學物質有降低趨勢，顯示列管後有助於降低環境濃度。本計畫分別以實地採樣水體、地下水擴散模擬結果、空氣擴散模擬結果進行鹽水溪流域之多介質與健康風險評估。魚體部份，大部份重金屬濃度推估值高於實測值；而底泥部份，大部份重金屬濃度實測值高於推估值。地下水擴散模擬之多介質與健康風險評估結果，以「魚類食入吸收」及「以地下水做為農作物灌溉用水，農作物吸收後人體食入吸收」為人體主要暴露途徑，致癌風險評估結果95% UL=1.45×10-5，非致癌風險95% UL HI=0.006。放流水源之健康風險評估結果，以「魚類食入吸收」為人體主要暴露途徑，致癌風險評估結果95% UL=7.90×10-4；非致癌風險95% UL HI=1.77。攝入戴奧辛的危害指標(Hazard Index, HI)，男、女性族群均以雲嘉南地區較高（男性：0.665，女性：0.610），均以宜蘭地區最低（男性：0.326，女性：0.272）。汞的危害指標男、女性族群均以高屏地區較高（男性：0.401，女性：0.395），男性以花東地區最低（男性：0.134），女性以竹苗地區最低（女性：0.099）。臺灣各地區的男性與女性族群，不論在吸入途徑或食入途徑，因暴露戴奧辛及汞所致之95％非致癌風險上限值仍在可接受範圍內（即HI<1）。

The major aims of this project were to (1) investigate concerned chemicals in fifteen Taiwanese rivers, (2) simulated distribution patterns of particular chemicals in a specific river, and (3) established managing and decision-making platform regarding distribution of chemicals. Sediment and fish samples were collected from fifteen Taiwanese rivers (i.e., Danshuei River, Sindian River, Dahan River, Keelung River, Dajia River, Jhuoshuei River, Bajhang River, Jishuei River, Shincheng River, Zengwun River, Gaoping River, Linbien River, Hualien River, Siouguluan River and Beinan River). Concentrations of hexachloro-1,3-butadiene (HCBD), short-chain chlorinated paraffins (SCCPs), nonylphenol (NP), bisphenol A (BPA), phthalate esters (PAEs), polybrominated diphenyl ethers (PBDEs), hexabrominated biphenyls (HBBs), polycyclic aromatic hydrocarbons (PAHs), heavy metal and methylmercury were determined in collected samples and 16,005 analyzed data were obtained. The concentrations of many analyzed chemicals in sediments decreased with time. The results indicated that the regulation to control usage of these chemicals is helpful to limit their releases into the environment. This project has evaluated the multiple media transport and health risk assessment in the Yanshuei river basin by metal concentrations of water sampling, in groundwater from simulation and air dispersion based on air pollution diffusion models. The results revealed that the estimated concentrations by the multiple media transport in fish were higher than the real samplings, but the simulated levels in sediment were lower than the real sampling for most metals. As the results of health risk assessment based on wastewater pollution simulations, the main exposure route was “eat fish” and “eat crops with water irrigation”. The cancer risk of 95% UL was 1.45 ×10-5; non-cancer risk of 95% UL HI was 0.006. Summary of health risk assessment based on wastewater pollution simulations, the main exposure route was “eat fish”, and cancer risk of 95% UL was 7.90 ×10-4; non-cancer risk of 95% UL HI was 1.77. Hazard index of oral intake on dioxin are highest in Yunjianan area in the male and female groups (male: 0.665, female: 0.610), and lowest in Yilan area (male: 0.326, female: 0.272). Hazard index of mercury are highest in Kaohsiung and Pingtung area in the male and female groups (male: 0.401, female: 0.395), lowest in the Huadong area in male (0.134), and lowest in female (0.099) in Hsinchu and Miaoli area. The non-carcinogenic risk due to exposure to dioxin and mercury is within the acceptable limits (ie HI<1) in male and female groups in all regions of Taiwan.