既有化學物質登錄資料缺口盤點及研析應用工作計畫
The Project for Inventory, Analysis, and Application of the Information on Existing Chemical Substances Registration

本計畫配合我國既有化學物質標準登錄制度實施，完成盤點106種指定既有化學物質標準登錄之物理與化學特性、毒理及生態毒理項目，盤點資料來源主要根據「既有化學物質標準登錄資料撰寫指引」中所列之國際公開資料庫，盤點結果依照物質特性提出分析報告並提供文獻索引或著作權等資訊。此外，根據資料盤點結果，提出5種具代表性物質的資料缺口填補策略，例如有機物質、無機物質、酸性物質、鹼性物質及含金屬物質。除資料盤點及分析外，本計畫亦研析中華民國國家標準 (National Standards of the Republic of China, CNS) 15030及化學品分類及標示全球調和制度第8版(Harmonized System of Classification and Labeling of Chemicals eight revised edition, GHS Rev.8)之差異，以及針對物理性危害、健康危害和環境危害項目完成29項與既有化學物質標準登錄相關之資料填寫及應用說明，並在GHS應用方面研析1種模擬混合物的危害分類方法及1份化學廠的安全資料表 (Safety Data Sheet, SDS)危害資訊傳遞。本計畫以強化既有化學物質標準登錄制度為主軸，最後提出3式毒理及生態毒理測試計畫書範本供登錄人參考使用。

Responding to implementation of the regulations of existing chemical substances standard registration, this project has collected the physiochemical, toxicological and eco-toxicological data of the designated existing chemical substances subject to standard registration. The international open access databases which apply to data collection were mainly from the guidance on existing chemical substances standard registration. This analysis report covered citation indexes, copyright information, and others according to substances properties. Also, some collection results were data lacking, therefore, the strategies of data gap filling for five typical substances, including an organic compound, an inorganic compound, an acid substance, a base substance, and a metal compound, have been conducted. In addition, this project not only shows the differences between National Standards of the Republic of China (CNS) 15030 and Globally Harmonized System of Classification and Labeling of Chemicals eight revised edition (GHS Rev.8) but also provides the advice to the preparation and application of the information of existing chemical substances standard registration in accordance with the physical, health, and environment hazards. At the same time, the hazard information transmission, based on GHS hazard identification, and the hazard classification methods of mixtures have been proposed. This project aims to strengthen the management of existing chemicals in accordance with the registration system of chemical substances. Three testing proposal examples of toxicology or eco-toxicology as the references for registrants have been finished as well.