本計畫延續97年度計畫，毒性化學物質許可證初審作業已成熟，並配合使用毒性化學物質許可管理系統之線上審查作業，確實執行完整初審步驟；本年度並著重於我國與國際間環境用藥法規規範的評析與建議。 本計畫完成重點工作包括： 1.毒化物許可技術審查作業，共審查申請件數191件，其審查天數新申請(平均審查5.1天)、展延(平均審查4.4天)、變更(平均審查4.1天)均符合合約規定審查期限。 2.完成辦理3場次毒性化學物質許可、登記、核可申請案技術審查說明會，共計73位地方環保人員參與。 3.收集美國、歐盟、中國大陸與新加坡等國際間環境用藥管理之法令規定，並分析5則環境用藥管理建議採行措施。 4.完成美國、新加坡環境用藥微生物製劑白殭菌(Beauveria bassiana Beauveria bassiana strain 447)、圓形芽孢桿菌(Bacillus sphaericus Serotype H5a5b strain 2362 ATCC 1170)註冊資料及菌種資料收集。 5.完成辦理環境用藥管理及病媒防治技術研討會，與會專家學者、環境用藥業者與相關科系研究生共計154人次參與。 本計畫除協助辦理毒化物許可審查初審作業外，並針對各國環境用藥管理相關法規進行評析，以提供環保署作為日後環境用藥法規制定趨勢參酌。

The preliminary review process for toxic chemical substances permit application has been fully established. The preliminary review has therefore been carried out online using the Toxic Chemical Substances Permit Management System to continue the efforts of the project in 2008. This year the focus is also on conducting analysis of domestic and international regulations governing environmental agents and providing recommendations accordingly. The important works completed are described as follows: 1.For technical review of toxic chemical substances permits, a total of 191 applications have been reviewed. Reviews of new (avg. 5.1 days), renewal (avg. 4.4 days), and change of details (avg. 4.1 days) applications were all conducted within the timeframe as required by the contract terms. 2.Three technical review sessions have been held for the applications of toxic chemical substances permit, registration, and approval, which was participated by 73 local environmental personnel. 3.Ordinances and regulations for environmental agent management practiced in the United States, the European Union, China, and Singapore have been collected. Analyses of 5 management cases and recommended measures have been proposed. 4.The collection of registration and strain data of the microbial preparations Beauveria bassiana strain 447 and Bacillus sphaericus Serotype H5a5b strain 2362 ATCC 1170 used as environmental agents in the United States and Singapore has been carried out. 5.The Conference on Environmental Agent Management and Vector Prevention and Control was held and attended by 154 participants including experts, scholars, businesses, and graduate students of related disciplines. The project provides assistance to the preliminary review of toxic chemical substances permit applications. Analyses of regulations pertaining to environmental agent management adopted by countries around the world have been also conducted to serve as reference for the EPA when formulating regulations in the future.