化學物質毒理資料庫建置及資訊管理計畫
Establishment and Information Management Plan of Chemical Substances Toxicology Database

完善的化學物質資訊與安全管理制度是先進國家發展指標之一,「毒性及關注化學物質管理法」,108 年 1 月 16 日經總統公布,使我國毒物及化學物質源頭管理工作再向前邁進,未來必須掌握列管物質重點之毒理資料,本計畫規劃提出資料庫格式欄位及維護管理作法,作為主管機關行政管制之支撐依據。依毒理資料庫前期規劃之產出結果,在「完成我國化學物質毒理資料庫發展整體架構建置」部分,完成化學物質毒理資料庫整體架構,並著手建置相關資訊欄位格式,及進行友善功能系統之設計,設計內容包含有「功能性檢索」「附件下載」「統計總表」及「響應式網頁」等。在「建立化學物質之毒理資料及規劃資訊管理方法」部分,研提優先納入毒理資料庫之資訊策略方針,評估毒性及暴露風險因子及配合化學局指定物質作為優先蒐集化學物質資料之對象,產出 90 項化學物質資料明細,並分析毒理資料參考來源,提出資料確核管理機制,其內容包含有「資料審查內容」及「資料審查程序」。另外,綜整實際使用操作與應用結果,評估資訊串聯及毒理資訊公開作法,包含有使用者分級功能、毒理資料辭典及相關參考資料庫連結。本計畫配合化學局行政實務及毒理資料庫推動事宜,已完成辦理2場次部會研商會議、1場次資料庫操作說明會及4場次毒理資料庫相關議題之專家學者諮詢會議。

Comprehensive chemical substances information and safety management systems are development indicators for advanced countries. To promote the managing efficiencies of the toxic substances and chemical substances from very beginning in Taiwan, the Toxic and Concerned Chemical Substances Control Act was promulgated by the President of ROC on January 16, 2019. In the future, it is necessary to grasp the toxicological information of the control substances. We have proposed the database format and the maintenance management practices as the supporting basis for the administrative control of the competent authority in this plan. Based on the results of Preliminary Planning of Chemical Substances Toxicology Database Project, we have completed the overall structure of the chemical substances toxicology database, and proceeded to build the format of relevant information fields, and design a friendly functional system. The designcontent includes "functional search", "attachment download", "statistics summary" and "responsive web design ". In the section of “Establishing Toxicological Information and Planning Information Management Methods for Chemical Substances”, we have developed the information strategy guidance. The guidance includes the toxicological data base, evaluate toxicity and exposure risk factors. Under the designation from the Toxic and Chemical Substances Bureau (TCSB), we have finished nighty chemical substances information and analyzed the toxicological data reference sources in this plan. Furthermore, we have proposed data verification management mechanism, including data examination verification and data examination procedure. Additionally, we summarize the methods of information connection and toxicology information by integrating actual operation and application results, including user classification functions, toxicology data dictionary and related database reference links.In assistance of the Toxic and Chemical Substances Bureau, this project had held two department-wide discussion meetings, one database operation instructions meeting, and four expert advisory meetings.